Genetics

How rare and common risk variation jointly affect liability for autism spectrum disorder.

Oligogenic combinations of rare variants influence specific phenotypes in complex disorders.

Temporal analysis of enhancers during mouse cerebellar development reveals dynamic and novel regulatory functions.

Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction.

SUPERGNOVA: Local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits.

Rates of contributory de novo mutation in high and low-risk autism families.

Genome-wide by environment interaction study of stressful life events and hospital-treated depression in the iPSYCH2012 sample.

Clinical autism subscales have common genetic liabilities that are heritable, pleiotropic, and generalizable to the general population.

Integrated gene analyses of de novo variants from 46,612 trios with autism and developmental disorders.

A panoramic view of proteomics and multiomics in precision health.

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