SFARI is working to advance autism science by providing a number of key resources to researchers. These include:
- Cohorts of well-characterized individuals with autism or with specific genetic alterations, including the Simons Simplex Collection (SSC), the Simons Variation in Individuals Project (Simons VIP), and SPARK.
- Tools that enable researchers to keep track of the genetic risk factors for autism (SFARI Gene).
- Data (including clinical, phenotypic, genetic, and neuroimaging data) and biospecimens from our sponsored research projects (SFARI Base).
- Tools that enable researchers to explore data from the SSC and Simons VIP, including the WuXi NextCODE SSC portal, the Genotype and Phenotype in Families tool and the Beacon Network.
- Induced pluripotent stem cell lines from SSC and Simons VIP participants.
- Autism mouse models that are readily available for researchers to order from The Jackson Laboratory.
- Autism rat models that are readily available for researchers to order from the Medical College of Wisconsin.
- Postmortem brain tissue for autism research (available through the collaborative network, Autism BrainNet).
- Therapeutics, including R-baclofen, for investigator-initiated studies in humans and animals (available from Clinical Research Associates, L.L.C., an affiliate of the Simons Foundation).