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  • Guest blog: A cautionary tale for autism drug development
    15 April 2014
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    Poorly designed animal drug studies for motor disorders have led to spurious conclusions for the clinical trials that follow. This may be even more true for autism research, says Michael Ehlers.

  • Molecular mechanisms: Gene marker may alter autism brains
    15 April 2014
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    In the brains of people with autism, certain genes are suppressed by a chemical tag that increases binding to MeCP2, the protein implicated in Rett syndrome. The findings were published 21 January in Translational Psychiatry.

  • No 'ideal' tissue for gene expression studies of autism
    15 April 2014
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    Researchers should investigate a broad spectrum of human- and animal-derived tissues to fully capture the complexity of autism, say Michael Talkowski and James Gusella.

  • Genetic background may alter behavior of autism mice
    14 April 2014
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    Differences in the background genetics of mouse strains may modify the effects of autism genes, suggests a study published 11 March in Autism Research. The study looked at the behavior of mice with a mutation in neuroligin-3, a strong autism candidate gene.

  • Study implicates obese fathers in children’s autism risk
    11 April 2014
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    The children of obese fathers may be at a 53 percent higher risk of autism than children whose fathers are a healthy weight, reports a large Norwegian study published 7 April in Pediatrics.

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