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Clinical research: Israeli study shows high autism prevalence

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Jessica Wright
5 October 2012

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Reduced rates: Thorough tests for autism may explain why children in Israel are diagnosed with the disorder less often than in the U.S.

A new study finds that 48 of every 10,000 children in Israel have autism. This rate, published 27 July in the Journal of Autism and Developmental Disorders, is higher than previous estimates for Israel, but lower than the reported U.S. prevalence1.

In March, the U.S. Centers for Disease Control and Prevention reported that 1 in 88, or about 114 per 10,000, children in the U.S. have autism. The reported prevalence in most other countries is significantly lower: For example, it is 27 per 10,000 in Brazil and 16 per 10,000 in China.

Explanations for this disparity include awareness of autism, the stigma associated with an autism diagnosis and differences in healthcare. 

How researchers estimate prevalence can also significantly alter the findings. For example, a 2011 study in South Korea that screened a representative sample of all children in a population found a prevalence of 264 per 10,0002. If the researchers had relied on existing medical records, however, the prevalence would have been 80 in 10,000.

Epidemiological studies of autism in Israel have reported relatively low rates. A 2001 study found an incidence of 10 for every 10,000 people3 and a 2012 study reported a prevalence of 36 per 10,000 people4. These studies relied on medical and healthcare records from treatment facilities and national organizations, such as the Israeli Ministry of Social Affairs.

In the new study, researchers used medical records from Maccabi Health Services, one of four health maintenance organizations that provide nationalized health services in Israel. They compared 2,034 children between 1 and 12 years of age who have an autism diagnosis with 421,490 others in the same age range.

Fewer children in low-income groups have a diagnosis of autism than do those from wealthier families, the study found. This trend is line with prevalence studies in the U.S., and may result from differences in awareness and cultural stigma, the researchers say.

Prevalence in Israel may be lower than in the U.S. because children in Israel undergo more thorough assessments for autism diagnosis, the researchers say. For example, each child in Israel undergoes two separate evaluations. Also, clinicians are required to describe how the child’s symptoms match the criteria for autism outlined in the Diagnostic and Statistical Manual of Mental Disorders.

References:

1: Davidovitch M. et al. J. Autism Dev. Disord. Epub ahead of print (2012) PubMed

2: Kim Y.S. et al. Am. J. Psychiatry 168, 904-912 (2011) PubMed

3: Davidovitch M. et al. Isr. Med. Assoc. J. 3, 188-189 (2001) PubMed

4: Gal G. et al. J. Autism Dev. Disord. 42, 428-431 (2012) PubMed

Comments

Name: Sarah
5 October 2012 - 3:27PM

I disagree with anaylisis of why autism rates are higher in the US than in lower income countries and I dont think it has any to do with differences in awarenes. I think there is a better explanation and it has to do with geopolitics and competition for global resources. Americans are large consumers of global resources and the US in direct competition with China for those dwindling resources. SO, how does that relate to autism increase? We get many of our goods including 80% of the active ingredients in our drugs from India and China. 80%!!! China has a very poor track record for public safety. Mass poisoning around the globe have been traced back to drug labs in China including one in Panama from toxic cough syrup laced with ethylene glycol (antifreeze) which killed many elderly. Chinese drug makers have been caught red handed substituting industrial chemcials for drug ingredients and selling them overseas. Perhaps it is time to investigate the quality of the drug ingredients shipped to the US from drug labs in China. Perhaps this explains the high autism rate in the US vs other countries. Perhaps China is using pharmaceuticals to weaken it's competition. Perhaps American children are being poisoned from toxic drug ingredients that is making them very sick. Sick children cannot compete.

For more info read: "Are We Sure Our Drugs Are Safe?" by John Dingell, US Representative and on FDA Oversight Committee for Drug Safety. Read "A Toxic Pipeline"- New York Times series on the poisonous drug trade from China. Also Watch "The Panama Syndrome" and "Dubai RX: Conduit for Fake Drugs" - two New York TImes investigative reports on China's toxic drug trade. Due to globalization, FDA cannot cotrol the flow. Our drug supply is not safe and neither are our kids.

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