Funded Projects
Understanding the cellular and circuit bases for behavioral impairments in the Scn2a knock-out rat
Awarded: 2022
Award Type: Targeted: Autism Rat Models Consortium
Award Type: Targeted: Autism Rat Models Consortium
CRISPR activation-based approach to rescue cellular and behavioral deficits associated with Scn2a haploinsufficiency
Awarded: 2019
Award Type: Director
Award Type: Director
Cellular and circuit effects of SCN2A haploinsufficiency
Awarded: 2017
Award Type: Pilot
Award Type: Pilot
SFARI Funded Publications
Cellular and behavioral effects of altered NaV1.2 sodium channel ion permeability in Scn2aK1422E mice.
Echevarria-Cooper D.M., Hawkins N.A., Misra S.N., Huffman A., Thaxton T., Thompson C.H., Ben-Shalom R., Nelson A.D., Lipkin A.M., George Jr. A. L., Bender K., Kearney J.A.
Physical and functional convergence of the autism risk genes Scn2a and Ank2 in neocortical pyramidal cell dendrites.
Nelson A.D., Catalfio A.M., Gupta J.M., Min L., Caballero-Florán R.N., Dean K.P., Elvira C.C., Derderian K.D., Kyoung H., Sahagun A., Sanders S., Bender K., Jenkins P.
CRISPR activation rescues abnormalities in SCN2A haploinsufficiency-associated autism spectrum disorder.
Tamura S., Nelson A.D., Spratt P.W.E., Kyoung H., Zhou X., Li Z., Zhao J., Holden S.S., Sahagun A., Keeshen C.M., Lu C., Hamada E.C., Ben-Shalom R., Pan J.Q., Paz J.T., Sanders S., Matharu N., Ahituv N., Bender K.