Guoping Feng, Ph.D.

James W. and Patricia T. Poitras Professor in Neuroscience, Massachusetts Institute of Technology

SFARI Investigator, SFARI Scientific Review Board Website

Guoping Feng is the James W. and Patricia T. Poitras Professor in Neuroscience at the McGovern Institute for Brain Research in the Department of Brain and Cognitive Sciences at the Massachusetts Institute of Technology and is a member of the Stanley Center for Psychiatric Research at the Broad Institute.

Feng’s research is focused on understanding synaptic mechanisms underlying psychiatric disorders. His lab has generated and characterized rodent models of autism spectrum disorders, obsessive-compulsive disorder and schizophrenia.

Funded Projects

Role of PTCHD1 in thalamic reticular nucleus function and autism

Awarded: 2014
Award Type: Research

Probing the neural basis of social behavior in mice

Awarded: 2012
Award Type: Pilot

Dissecting the circuits underlying autism-like behaviors in mice

Awarded: 2010
Award Type: Research

SFARI Funded Publications

Viral manipulation of functionally distinct interneurons in mice, non-human primates and humans. Vormstein-Schneider D.C., Lin J.D., Pelkey K.A., Chittajallu R., Guo B., Arias-Garcia M.A., Allaway K., Sakopoulos S., Schneider G., Stevenson O., Vergara J., Sharma J., Zhang Q., Franken T.P., Smith J., Ibrahim L.A., Astro K.J.M., Sabri E., Huang S., Favuzzi E., Burbridge T., Xu Q., Guo L., Vogel I., Sanchez V., Saldi G.A., Gorissen B.L., Yuan X., Zaghloul K.A., Favuzzi E., Devinsky O., Sabatini B., Batista-Brito R., Reynolds J., Feng G., Fu Z., McBain C.J., Fishell G., Dimidschstein J.

Combinatorial targeting of distributed forebrain networks reverses noise hypersensitivity in a model of autism spectrum disorder. Nakajima M., Schmitt L.I., Feng G., Halassa M.

Research Highlight

Targeting peripheral somatosensory neurons to improve tactile-related phenotypes in ASD models. Orefice L., Mosko J.R., Morency D.T., Wells M.F., Tasnim A., Mozeika S.M., Ye M., Chirila A.M., Emanuel A.J., Rankin G., Fame R.M., Lehtinen M., Feng G., Ginty D.

Research Highlight