The mitochondrial genome encodes genes critical for energy production within the brain. Many lines of evidence suggest that mitochondrial function may be impaired in autism. Neal Sondheimer will evaluate the association between mitochondrial mutations and their interactions with the nuclear genome and the risk for autism.
SFARI science staff will be presenting a number of posters about SFARI projects and resources at the International Society for Autism Research (INSAR) 2018 Annual Meeting in Rotterdam, Netherlands (May 9-12).
Yann Herault is a neurobiologist studying the pathophysiology of neurodevelopmental disorders at the French National Centre for Scientific Research (CNRS).
SPARK is an online research initiative that aims to recruit 50,000 individuals with autism and their family members living in the U.S.
The neuron-specific potassium-chloride co-transporter, KCC2, is involved in the regulation of excitatory and inhibitory neuronal activity. It has been identified as a promising therapeutic target for autism. In the current project, Charles Craik’s laboratory and collaborators plan to determine the high-resolution structure of KCC2 with the intention of developing strategies to regulate its activity.
SFARI is pleased to announce that it has awarded 13 grants in response to the Explorer Awards request for applications this year.
SFARI is pleased to announce that it has awarded 32 grants (19 Pilot Awards and 13 Research Awards) in response to the 2017 Pilot and Research Awards request for applications (RFA).