Simons Simplex Collection

Beliefs in vaccine as causes of autism among SPARK cohort caregivers.

Predictive impact of rare genomic copy number variations in siblings of individuals with autism spectrum disorders.

Transcriptome-wide transmission disequilibrium analysis identifies novel risk genes for autism spectrum disorder.

Elevated polygenic burden for autism spectrum disorder is associated with the broad autism phenotype in mothers of individuals with autism spectrum disorder.

De novo damaging DNA coding mutations are associated with obsessive-compulsive disorder and overlap with Tourette’s disorder and autism.

Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders

Disruptive variants of CSDE1 associate with autism and interfere with neuronal development and synaptic transmission.

Social and non-social autism symptoms and trait domains are genetically dissociable.

Primary complex motor stereotypies are associated with de novo damaging DNA coding mutations that identify candidate risk genes and biological pathways.

Inherited and de novo genetic risk for autism impacts shared networks.

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