Pamela Sklar, is a neuroscientist, human geneticist and clinical psychiatrist investigating the genetic causes of psychiatric disorders, including schizophrenia and bipolar disorder. A major focus of her prior work has been identifying risk genes for psychiatric diseases by applying tools for understanding and characterizing variation in the human DNA sequence. 

Currently, she is chief of the Division of Psychiatric Genomics and professor of psychiatry, neuroscience, genetics and genomic sciences at Icahn School of Medicine at Mount Sinai Hospital in New York. Sklar received both her Ph.D. in neuroscience and her M.D. from Johns Hopkins University School of Medicine.