Marta Biagioli is an associate processor of genetics at the University of Trento. A molecular biologist by training, she has expertise in RNA regulation, non-coding RNAs and genome-wide approaches in the context of genetic neurological diseases.
As a trainee in the laboratory of Stefano Gustincich, Biagioli contributed to the discovery of a new class of non-coding “antisense” RNAs, key regulators of the protein stability of their “sense” counterpart. This pioneering work that paved the way to SINEUP technology, an innovative tool for treating haploinsufficiencies. Later, at the Center for Human Genetic Research at Massachusetts General Hospital and Harvard Medical School in Boston, she expanded her research to human genetics, with a particular focus on autism and Huntington’s disease.
Biagioli has held her position in the University of Trento’s Department of Cellular, Computational and Integrative Biology since November 2014. Her laboratory focuses on the characterization of epigenetic basis of complex brain functions and how alterations in chromatin remodelling complexes, histone modifications patterns and non-coding RNAs might contribute to neurodegenerative and neurodevelopmental conditions.