María Domercq completed her Ph.D. and postdoctoral training working in the laboratories of C. Matute and A. Volterra on the role of glial cells in neurodegenerative conditions. After completing a tenure track research program with a “Ramon y Cajal” post, she transitioned to independent research as an associate research professor at the Department of Neuroscience in the School of Medicine at the University of the Basque Country (Leioa, Spain). She is also a group leader at the Achucarro Basque Center for Neuroscience (Leioa, Spain).

Domercq’s laboratory focuses on understanding how oligodendrocytes are damaged in demyelinating diseases and in designing new strategies to improve endogenous brain capacity for myelination/remyelination. Her group has made important contributions in the field of multiple sclerosis, the primary demyelinating disease. More recently, in collaboration with O. Peñagarikano, she began working on myelination during development in autism. Her team uses state-of-the-art techniques to analyze myelination and its impact on physiology and pathology including cellular and molecular biology, chemogenetics, AVV viral injections, STED confocal microscopy, two-photon imaging, electrophysiology, behavior and lipidomics and transcriptomics analysis.