Kartik Pattabiraman, M.D., Ph.D.
Assistant Professor, Yale Child Study Center
SFARI Investigator WebsiteKartik Pattabiraman is an assistant professor at the Child Study Center at Yale University. He received his M.D. and Ph.D. from the University of California, San Francisco, where he completed his graduate studies in the laboratory of John Rubenstein. He completed his adult psychiatry residency and child and adolescent psychiatry fellowship at Yale University. During his clinical training, he worked in the laboratory of Nenad Sestan.
The long-term goal of the Pattabiraman laboratory is to confidently identify infants who will develop neurodevelopmental or neuropsychiatric conditions prior to the onset of symptoms and mitigate/prevent these symptoms. Early diagnosis will be achieved by integrating an individual’s genetic and functional genomic data with a mechanistic understanding of human cortical development. Early life interventions will focus on targeting specific circuit disruptions identified by an individual’s genetic risk factors.
Basic research in his laboratory aims to understand the fundamental neurodevelopmental processes required to achieve these goals. Specifically, the Pattabiraman laboratory is studying the mechanisms of cortical circuit assembly active in human mid-fetal cerebral cortex, including characterizing transient early cortical circuits which serve as the scaffold for subsequent cortical connectivity. Additionally, the laboratory is interested in studying the effect of environmental and genetic risk factors on cortical development and connectivity.