Harrison Gabel is an associate professor of neuroscience at Washington University in St. Louis. He received an A.B. in molecular biology from Princeton University and a Ph.D. in genetics from Harvard Medical School. Since establishing his laboratory in 2015, he has studied epigenetic mechanisms in the brain and investigated how disruption of these mechanisms can lead to autism and related neurodevelopmental disorders. Gabel’s group has identified new mechanisms of gene regulation mediated by a unique form of neuron enriched non-CpG DNA methylation and the Rett syndrome protein MeCP2 and shown that this gene regulatory pathway is susceptible to disruption across multiple genetic causes of autism spectrum disorder (ASD). His ongoing work is exploring the potential for molecular convergence across epigenetic ASD genes. Gabel’s lab is utilizing emerging genomic technologies to decipher the impact of mutations in these genes on gene expression and neuroanatomy at cellular resolution in the brain.