Christopher K. Glass is professor of cellular and molecular medicine and professor of medicine at the University of California, San Diego School of Medicine.
Glass’ lab investigates transcriptional mechanisms that regulate the development and function of the macrophage, a cell that plays key roles in immunity and inflammatory diseases. Current efforts are to determine the biochemical and biological roles of sequence-specific transcription factors and their associated co-regulators at gene-specific and genome-wide scales. A combination of biochemical, cellular and genetic model systems are used, incorporating macrophage-specific knockouts, microarray technologies, massively parallel sequencing and bioinformatics approaches to unravel the contributions of specific factors to the development of specialized macrophage functions in immunity and the pathogenesis of inflammatory diseases.
Glass is an elected member of the National Academy of Sciences, National Academy of Medicine and the American Academy of Arts and Sciences.