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Events

Upcoming Events

SFARI Clinical and Basic Researcher Speed Networking at INSAR 2025

The Simons Foundation Autism Research Initiative (SFARI) is hosting an event focused on bringing together basic science and clinical researchers for speed networking. The event is intended for doctoral-level scientists (e.g., PIs and senior postdocs) attending the 2025 annual INSAR meeting. We hope this event will foster better understanding of different disciplines and potentially create new opportunities for collaboration. SFARI staff will also be available to answer any questions you may have about the research and resources supported by SFARI.

Past Events

Autism genetics: Where have we been and where are we going?

Matthew State, M.D., Ph.D.Oberndorf Family Distinguished Professor and Chair, University of California, San Francisco

On April 10, 2018, Matthew State reviewed the progress that has been made in autism genetics over the past 10 years and the role that the Simons Simplex Collection (SSC) played in this (r)evolution. He also addressed the potential contribution of ongoing genomic studies including whole-genome sequencing as well as the challenges and opportunities of leveraging the genetic findings to identify pathophysiological mechanisms.

Portrait of Investigator Shafali Spurling Jeste.

On the road to precision health: Brain-based biomarkers in autism spectrum disorder

Shafali Spurling Jeste, M.D.Chief, Division of Neurology, Children’s Hospital Los Angeles
Professor of Neurology and Pediatrics, Keck School of Medicine, University of Southern California

On 7 February 2018, Shafali Spurling Jeste provided a topical overview of the current state of research in autism biomarkers. She shared data from studies of autism biomarkers in three key areas: early risk prediction (studies of high-risk infants), heterogeneity within the autism spectrum and genetically defined subgroups within autism. Finally, she discussed the challenges around clinical trial design and development and considered how more objective measures of brain function can improve clinical trials.

Headshot of Investigator Matthew Siegel.

Arousal, emotion regulation and challenging behaviors: Insights from the Autism Inpatient Collection

Matthew Siegel, M.D.Associate Professor, Tufts University
Chief of Clinical Enterprise, Boston Children’s Hospital

On 24 January 2018, Matthew Siegel drew upon a new resource, the Autism Inpatient Collection data set, to offer preliminary insights into the relationships between physiologic arousal, emotion dysregulation and the occurrence of challenging behaviors. Such behaviors may represent an attempt to modulate physiologic arousal in minimally verbal individuals with autism spectrum disorders.

Portrait of SFARI Investigator Daniel Geschwind.

Autism genetics: Searching for coherence

Daniel Geschwind, M.D., Ph.D.Gordon and Virginia MacDonald Distinguished Professor of Neurology, Psychiatry and Human Genetics, University of California, Los Angeles

On 28 November 2017, Daniel Geschwind discussed his group’s use of RNA sequencing, chromatin structure and gene networks to help develop an understanding of potential convergent mechanisms in autism spectrum disorders.

Understanding autism and other neurodevelopmental disorders: From the embryo to brain organoids

Paola Arlotta, Ph.D.Professor, Harvard University

On 1 November 2017, Paola Arlotta focused on the cerebral cortex and presented the challenges and opportunities of modeling human brain development using pluripotent stem cells within 3D human brain organoids. Building on developmental work in mice, such organoids promise a better understanding of complex neurodevelopmental conditions such as autism spectrum disorder.

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