On April 24, 2019, David Ginty presented his work on the neurobiological basis of touch over-reactivity in mouse models of autism spectrum disorders (ASD). He also discussed new pharmacological approaches aimed at reducing sensory over-reactivity and potentially improving cognitive and behavioral abnormalities associated with ASD.
His talk was part of the Simons Foundation Autism Research lecture series.
About the Lecture
Mounting evidence indicates that sensory processing impairments are a key feature of ASD. In this lecture, David Ginty described work that employs molecular genetics, electrophysiological, synaptic and behavioral analyses to define the neurobiological basis of touch over-reactivity in mouse models of ASD, and its relationship to brain development and ASD-associated behavior. He also discussed new pharmacological approaches to treat touch over-reactivity with the goal of reducing sensory over-reactivity and potentially improving cognitive and behavioral abnormalities associated with ASD.
About the Speaker
David Ginty is the Edward R. and Anne G. Lefler Professor of Neurobiology at Harvard Medical School and an investigator of the Howard Hughes Medical Institute. His research focuses on development and functional organization of neural circuits that underlie touch perception in normal and disease states, and he serves as associate director of Harvard’s Program in Neuroscience. Ginty is an elected member of the National Academy of Sciences and the American Academy of Arts and Sciences.
