SFARI Base is a central database of clinical and genetic information about families affected with autism, provided as part of the Simons Foundation Autism Research Initiative (SFARI). At present, the database contains phenotype data from the SFARI Simplex Collection. As of November 2009, SFARI has recruited more than 1,500 families into the simplex collection and we will add roughly 200 new families every three months. You can review the list of instruments used in the SSC. For additional information about the collection, please review the Researcher Welcome Packet. Parallel genome-wide scans of the collection are being carried out by Dr. Mike Wigler at CSHL (using a Nimblegen platform) and Dr. Matthew State at Yale University (using an Illumina platform). Their findings will be incorporated into future data distributions as they become available. Approximately 4,000 to 6,000 phenotypic data points are available for each SSC family; these variables are defined in the available Data Dictionary. All information related to phenotype data and biological materials has been de-identified, i.e., recorded in such a manner that subjects cannot be identified, directly or through identifiers linked to the subjects (see CFR 45 Part 46.101(b)). The Institutional Review Protocol governing this collection is available, as is an example of a consent form used at one of the collection sites. This collection is publicly available to researchers through an application process. |