Conference Reports

  • Speaking volumes: Manually defining amygdala borders, scientists have found that the larger the size of the region, the worse a child's language ability.
    conference report

    A child's language ability correlates with the volume of his or her amygdala — the small, deep brain region that is strongly associated with emotional processing — according to an unpublished five-year longitudinal study presented Wednesday afternoon at the Society for Neuroscience meeting.

    Analyzing brain imaging data collected from 24 infants at...

    21 Nov 2008 .:. 0 comments
  • How do I ape thee: Children with autism rely on 'action-constrained' neurons to perceive others' actions, scientists say.
    conference report

    High-functioning children with autism may understand another person’s intention when, for example, that person reaches for a glass of water — a simple, goal-directed task — without help from the mirror neuron system, according to research reported Tuesday at the Society for Neuroscience meeting.

    Some researchers have proposed that mirror neurons —...

    20 Nov 2008 .:. 0 comments
  • On target: Researchers are studying mouse retinas to uncover the genes that help neurons find their synaptic partners.
    conference report

    Researchers are narrowing in on a pool of genes that may be involved in helping neurons find their targets, according to unpublished work presented today in a poster session at the Society for Neuroscience meeting.

    The work focused on neurons in the mouse retina, the inner layer of the eye, but has...

    19 Nov 2008 .:. 0 comments
  • Dopamine drug: Risperidone is used to treat irritability in children and adolescents with autism.
    conference report

    A new slow-release form of the drug risperidone — an antipsychotic given to people with schizophrenia, autism and other psychiatric conditions — lasts in the blood days instead of hours, according to research presented today at the Society for Neuroscience meeting.

    Risperidone inhibits dopamine signaling in the brain, and the U.S. Food...

    19 Nov 2008 .:. 0 comments
  • Micro effects: Some microRNAs are under expressed in schizophrenia and bipolar disorder.
    conference report

    Some small fragments of RNA, called microRNAs, are under-expressed in people with schizophrenia and bipolar disorder compared with controls, according to unpublished research based on postmortem brain tissue presented this morning at the Society for Neuroscience meeting.

    Schizophrenia and bipolar disorder each affect about one percent of the population, and recent genetic...

    19 Nov 2008 .:. 0 comments
  • Diverse paths: Studying mechanisms of plasticity in inhibitory synapses has uncovered some surprises.
    conference report

    The molecular mechanisms underlying synaptic plasticity — the ability of neurons to change the strength of their connections — can vary across different inhibitory neural circuits as much as they can vary across excitatory neural circuits, according to research presented this morning at the Society for Neuroscience meeting.

    Uncovering these mechanisms could...

    18 Nov 2008 .:. 0 comments
  • Dense dendrites:  Lithium decreases the length and density of dendritic spines in a mouse model of fragile X.
    conference report

    Lithium treatment reverses some of the behavioral and brain-cell abnormalities in mouse models of fragile X syndrome — an inherited form of mental retardation that includes learning deficits, aggressiveness, and social withdrawal — according to research presented today at the Society for Neuroscience meeting.

    Doctors have for about 50 years prescribed lithium...

    18 Nov 2008 .:. 0 comments
  • Single source: Stem cells derived from the skin can form nerve cells and be used to study autism.
    conference report

    A team of scientists is reprogramming adult stem cells generated from tiny skin samples of people with autism to form nerve cells, creating a powerful research tool for the disorder.

    Exposed to the correct transcription proteins, skin cells can transform into pluripotent stem cells — which, in turn, can be prompted to...

    18 Nov 2008 .:. 0 comments
  • Beyond genes: Epigenetic modifications may help explain learning and memory deficits in disorders such as schizophrenia and autism.
    conference report

    Targeting epigenetic mechanisms may offer potential new therapies for people with developmental disorders including autism, researchers said today at the Society for Neuroscience meeting.

    Epigenetics refers to modifications of the DNA sequence, such as the addition of a methyl group, that can alter gene expression without changing the sequence. Environmental factors such...

    17 Nov 2008 .:. 0 comments
  • Not-so-simple setup: Unlike the new 'licking test', most behavioral tests for mice require them to perform unnatural actions.
    conference report

    Researchers at the Society for Neuroscience today described a new test for animal behavior that doesn't interfere with normal mouse behavior, doesn't require human interaction, and makes it simple to take long-term measurements: the ‘licking test’.

    Best of all, the new test seems to differentiate between two models of Angelman syndrome that...

    17 Nov 2008 .:. 0 comments