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  • Behavioral therapy normalizes activity in autism brains
    2 May 2013
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    Pivotal response training, a form of behavioral therapy for autism, alters brain activity in children with the disorder, normalizing it in some regions and triggering compensatory activity in others, according to a small study. The unpublished results were presented Wednesday at the International Meeting for Autism Research in San Sebastián, Spain.

  • Lack of corpus callosum yields insights into autism
    2 May 2013
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    A rare birth defect offers a unique perspective on the connectivity theory of autism. Up to one-third of those missing all or part of the corpus callosum, a thick tract of nerve fibers connecting the left and right brain hemispheres, meet the diagnostic criteria for autism, several recent studies suggest.

  • Light toggles function of signaling proteins
    1 May 2013
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    Researchers can use light to activate certain proteins that receive signals at the junctions between neurons and that are key targets for fragile X syndrome therapies, according to a study published in the April issue of Nature Neuroscience.

  • Guest blog: Shared genetic risk
    30 April 2013
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    A large study identifying common genetic variations that contribute to five different psychiatric disorders, including autism, sheds light on the disorder’s genetic architecture, says Benjamin Neale.

  • Reactions from IMFAR
    30 April 2013
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    We check in from the 2013 International Meeting for Autism Research with daily reactions from this year’s attendees.

New RFAs

SFARI has two new targeted RFAs, one on circuit dynamics and one on Simons VIP biospecimens.

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Connectivity

This special report examines the theory that neural connectivity is altered in autism, exploring the latest findings and debates in the field.