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  • No 'ideal' tissue for gene expression studies of autism
    15 April 2014
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    Researchers should investigate a broad spectrum of human- and animal-derived tissues to fully capture the complexity of autism, say Michael Talkowski and James Gusella.

  • The cerebellum's surprisingly evolved role in autism
    1 April 2014
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    Thought until recently to only coordinate motor skills, the cerebellum is involved in diverse cognitive functions such as language and social interaction, and may play a role in autism, says Emanuel DiCicco-Bloom.

  • Emerging importance of chromatin in autism risk
    18 March 2014
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    Sequencing studies over the past few years have made a dramatic and unexpected discovery: Many of the mutations in individuals with autism are in genes that regulate chromatin, which helps package DNA in the cell nucleus, say Gerald Crabtree and Aryaman Shalizi.

  • No longer junk: Role of long noncoding RNAs in autism risk
    4 March 2014
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    Long pieces of RNA that do not code for protein have diverse and important roles in the cell and may contribute to autism risk, say Nikolaos Mellios and Mriganka Sur.

  • Intense world theory raises intense worries
    21 January 2014
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    The ‘intense world theory’ of autism, which has attracted much interest from the popular press, has received very little academic scrutiny. Uta Frith and Anna Remington ask: Is it as positive as it purports to be, and what does it mean for autism?

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