30 November 2011Comments ( 0 )
Regions of the genome that contain the same genetic variants on both copies of a chromosome are more likely to contain autism-associated genes than other parts of the genome, according to a study published 14 October in Human Genetics.
23 November 2011Comments ( 2 )
Researchers have derived neurons from stem cells to investigate mutations that lead to Rett and fragile X syndromes.
16 November 2011Comments ( 0 )
Researchers have engineered 20 mouse lines that allow them to manipulate genes in specific neuronal circuits. The resource, reported 22 September in Neuron, will allow researchers to better explore the role of interneurons, which dampen signals in the brain, in mouse models of autism.
9 November 2011Comments ( 0 )
Researchers have sequenced 17 laboratory mice and mapped 56.7 million single-base DNA variants in their genomes, according to a study published 15 September in Nature. A companion paper in the same issue identifies more than 700,000 structural variants, which are insertions, deletions or other modifications of DNA.
2 November 2011Comments ( 0 )
A technique for detecting gene expression that detects short RNA messages is better suited than traditional methods for analyzing postmortem brain tissue, according to a study published 10 September in BMC Genomics.