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  • New behavioral test uncovers autism mouse's stubbornness
    2 October 2013
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    Researchers have developed a new test that reveals complex repetitive behaviors in BTBR mice, a mouse strain with features resembling those of autism, according to a study published 27 August in the Journal of Neuroscience Methods.

  • New method uses light to toggle gene expression
    25 September 2013
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    Researchers have modified optogenetics — a technique that activates neurons in mouse brains with beams of light — to toggle a gene on or off. They reported the advance 22 August in Nature.

  • Rett syndrome mutation alters motor function in zebrafish
    18 September 2013
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    Mutating MeCP2, the gene linked to Rett syndrome, in zebrafish allows researchers to investigate the disorder early in development, according to a study published 16 July in Frontiers in Neural Circuits.

  • Technique probes gene expression in intact tissue
    11 September 2013
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    A new method allows researchers to highlight mutations in individual cells without first isolating the cells from the surrounding tissue, according to a study in the August Nature Methods.

  • Rats armed to catch up to mice as top mammalian model
    4 September 2013
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    Researchers have developed a method to engineer rats so that they lack a certain gene in only select regions of the brain, they report in the July issue of Nature Methods.