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Combining functional magnetic resonance imaging of rat brains with a technique that uses light to detect neuronal activity can help researchers hone in on the source of the activity, according to a study published 6 May in Nature Methods.

Researchers have created sponge-like assemblies of hundreds of thousands of short fragments of RNA, which can be used to dampen the expression of certain genes, according to a study published 26 February in Nature Materials.

A biological signature in the blood could be used to aid the early diagnosis of schizophrenia, according to a study published 12 April in Molecular Psychiatry. The results suggest that various circulating immune molecules and metabolites reflect the biological changes that underlie neurological disorders.

Researchers are developing a resource that will allow scientists to engineer mice lacking one of 162 microRNAs — non-coding regions of the genome that regulate gene expression. The results were published 19 April in Cell Reports.

By manipulating the location of a protein that detects capsaicin, the molecule responsible for the burn in hot chili peppers, researchers can activate subpopulations of neurons and alter the behavior of mice. The results were published 20 March in Nature Communications.