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  • Autism shares features with cerebellar syndromes
    3 December 2009
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    There are clinical, anatomical and genetic overlaps between autism and certain rare developmental disorders of the cerebellum, and these disorders may help understand autism, according to several studies published in the past year.
  • Baby sib studies reveal differences in brain response
    30 November 2009
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    Studies on younger siblings of children with autism are finding that during tests of sensory or perceptual processing, these baby sibs show abnormally fast brain responses, rather than a delay.
  • Loss of inhibitory neurons marks autism mouse models
    24 November 2009
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    Autism may be the result of faulty wiring that occurs during early brain development, according to two independent studies that looked at the origins of circuit disruption.
  • Only subset of chromosome 16 variants linked to autism
    20 November 2009
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    Deletions or duplications of chromosomal segment 16p11.2 — previously reported as a key autism region — are seen in people with developmental delays and speech and behavioral problems, but not necessarily autism. That's the finding from two large studies published last week of people carrying these rare genetic variations.
  • MeCP2 loss leads to smaller neurons in brain region
    18 November 2009
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    Deleting MeCP2, the gene that's mutated in Rett syndrome, alters both the size and function of neurons in the mouse brain — at least in one brain region, the locus ceruleus — according to a September 30 report in the Journal of Neuroscience.
New RFAs

SFARI has two new targeted RFAs, one on circuit dynamics and one on Simons VIP biospecimens.

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Connectivity

This special report examines the theory that neural connectivity is altered in autism, exploring the latest findings and debates in the field.