19 September 2013Comments ( 1 )
Small regulatory RNA molecules are most active between infancy and early childhood in a region of the brain known for complex thinking and behavior, reports a new study published 6 August in Molecular Psychiatry. The finding, based on an analysis of postmortem brains, may provide insight into what goes wrong in neurodevelopmental disorders such as autism.
16 September 2013Comments ( 14 )
Enzymes called topoisomerases are crucial for the expression of extremely long genes, including many that have been linked to autism, according to a study published 5 September in Nature. The researchers also discovered that autism genes are, on average, significantly longer than others.
12 September 2013Comments ( 15 )
Children who have older siblings with autism are seven times more likely than those in the general population to receive autism diagnoses themselves, according to a large Danish study published 19 August in JAMA Pediatrics.
9 September 2013Comments ( 0 )
Depleting excess levels of a molecule involved in neuronal signaling prevents the cognitive and motor symptoms of Angelman syndrome in a mouse model of the disorder, according to a report published 15 August in Cell Reports.
5 September 2013Comments ( 0 )
Thanks to a suite of new tools based on synthetic biology, it's now possible to quickly and cheaply insert autism-linked mutations into living cells in the lab.