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  • Signaling imbalance may underlie tuberous sclerosis complex
    17 June 2013
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    The mutation that causes tuberous sclerosis complex, an autism-related disorder, may disable calming signals in the brain, leading to hyperactive neurons, according to a study published 8 May in Neuron.

  • Imaging reveals more folds, thicker cortex in autism brains
    13 June 2013
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    The brains of people with autism are structurally different from those of controls, with more folds and a thicker cortex in certain regions, according to two studies published in the past few months.

  • New imaging techniques probe brain's long-range connections
    10 June 2013
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    New techniques to scan the brain can produce exquisitely detailed views of white matter, which contains the long cellular fibers that connect neurons. Many of the advances are emerging from the Human Connectome Project, a five-year push to map the brain’s wiring.

  •  Study uncovers molecular targets of autism-linked RORA gene
    6 June 2013
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    RORA, an autism candidate gene, encodes a protein that binds more than 2,500 other genes and alters the expression of some of those genes, according to a study published 22 May in Molecular Autism.

  • Mouse model mimics mosaic mutation in tuberous sclerosis
    3 June 2013
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    Deleting both copies of a gene linked to tuberous sclerosis complex, an autism-related disorder, in only a subset of brain cells recapitulates many of the disorder’s symptoms in mice, according to a study published 9 May in Neuron.

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