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In Brief

  • Genetics: Gene variants modulate Rett symptoms
    30 April 2013
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    A single gene mutation leads to Rett syndrome, but other variants may modify the severity of an individual's symptoms, according to a study published 28 February in PLoS One.

  • Clinical research: Short test finds autism traits in families
    26 April 2013
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    A 36-question survey detects features of autism in as much as 23 percent of parents of children with autism and 9 percent of control parents, researchers reported 20 February in Autism Research.

  • Molecular mechanisms: Maternal antibodies boost brain size
    23 April 2013
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    Maternal antibodies that raise the risk of autism when a fetus is exposed to them in utero may lead to elevated head size in the child, according to a study published 8 February in Brain, Behavior and Immunity.

  • Cognition and behavior: 'Mind blindness' has brain signature
    19 April 2013
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    People with autism, unlike controls, do not show distinct patterns of brain activity when evaluating scenarios that require them to infer others’ thoughts, according to two studies published in the past two months.

  • Genetics: Regulatory RNAs found in autism risk regions
    16 April 2013
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    Chromosomal duplications or deletions may influence autism-linked genes indirectly, by altering fragments of RNA that regulate gene expression, according to a study published 25 February in PLoS One

New RFAs

SFARI has two new targeted RFAs, one on circuit dynamics and one on Simons VIP biospecimens.

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Connectivity

This special report examines the theory that neural connectivity is altered in autism, exploring the latest findings and debates in the field.