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Video: A landscape view of DNA modifications

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Sarah DeWeerdt
14 November 2011

Just when we were wrapping our minds around the genome, along came the transcriptome, the proteome, the connectome and several other ‘–omes’ that became the focus of intense scientific investigation.

Earlier this year, Janine LaSalle led the first comprehensive analysis of the methylome, the genome-wide pattern of methylation, in human neurons.

Methylation involves the addition of a methyl group to DNA, turning genes on and off. Mapping methylation patterns can lend insight into the function of cells and how they might be affected by environmental factors.

At the 2011 Society for Neuroscience annual meeting in Washington, D.C., LaSalle, professor of medical microbiology and immunology at the University of California, Davis, made a case for the importance of the methylome in autism research.

For more reports from the 2011 Society for Neuroscience annual meeting, please click here.


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